Effect of Increasing Dose of Methacholine on Gastric Acid Secretion
نویسندگان
چکیده
It was reported that commercial preparations of both secretin and pancreozymin inhibit gastric acid secretion (Greenlee, Longhi, Guerrero, Nelsen, El-Bedri, and Dragstedt, 1957; Gillespie and Grossman, 1964). Pancreozymin (PZ), in addition, inhibits gastric motility (Johnson and Magee, 1965). Magee and Nakamura (1966), in a preliminary report, have noted that gastric acid is inhibited readily in conscious dogs only when large doses of PZ are used. With small doses, on the contrary, gastric acid secretion is stimulated.
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